The completely solid-state EchoTherm IC25 Digital, Programmable, Electronic Chilling/Heating Dry Bath is versatile, reliable and easy to use. The IC25 has simple digital controls and a two-line alphanumeric display that is backlit for easy reading. The display shows both the target and actual temperatures. Additionally, it displays the timer and all programming functions.

The chilling/heating surface is a 2.875” (7.3 cm) x 4.375” (11.1 cm) aluminum plate that is very flat for optimal contact with the sample. When unloaded, the plate will go below 0°C in under two minutes. It will heat to 37°C in even less time. Generally, the unloaded surface will decrease temperature at about 3°C/minute. Heating rates on the unloaded plate are usually about 5°C/minute. The blocks sold as accessories range in size and mass depending upon the samples used. The unit can drive a block for 1.5 ml centrifuge tubes from ambient temperature to 4°C in less than 30 minutes. When used with an accessory cover these blocks can be driven below 0°C. Temperature gradients from the center to the edge of any accessory block will be less than 0.5°C at any temperature.

Optional Models

• XT Model: Chilling range expanded to -20°C without sample block. Recommended for holding samples steady at low temperatures without cycling. 
• XR Model: dual Peltier modules for extra power, faster speeds between temperatures and expanded heating to 110°C without sample block. Strongly recommended for larger loads and for cycling temperatures up and down.

Features

• 5-program memory
• Energy-efficient Peltier design
• Digital control to 1°C from -20°C to 110°C without sample block
• Control at ambient
• Built-in data logger
• Count down timer (up to 30 days) with audible alarm and user settable Auto-Off
• RS232 I/O port for data collection
• Electronic calibration. Factory set, but user can set to any local standard
• Small, compact size. Uses very little bench space
• 12-volt DC operation. External power supply provided
• 12-month warranty
• UL, CSA and CE compliant

Applications Include

• Unattended restriction digestions or ligations at elevated temperatures then reducing temperature to 4°C automatically to reduce non-specific nuclease digestion of target DNA
• Automatically stopping reactions by having the unit reduce sample temperature after a specific reaction time
• Producing denatured probes or single stranded DNA molecules by heating to 90°C to 95°C for a given time and rapidly reducing temperature to 4°C to prevent renaturation
• Automatic temperature profiles to grow bacteria at 37°C, then increasing temperature to induce events, and then lowering temperature to 4°C to prevent degradation
• Maintaining 14°C for ligation reactions
• Enzyme reactions and deactivations
• Maintaining 17°C for storing oocytes
• Storing reagents at 4C in 15, 50, 250, and 500ml centrifuge tubes
• Storing samples at ice bucket temperatures without the mess
• Incubating samples at 37°C in 96-well assay plates or in aluminum blocks holding 0.2, 0.5 and 1.5 ml centrifuge tubes, vials, and test tubes
• Storing enzyme or DNA libraries at your workstation
• Freezing and storing most any sample at your workstation